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Upper Gastrointestinal Trials 

 

Please see below to view the upper gastrointestinal trials taking place within the Peninsula Cancer Network

 

ASPECT

Description:

ASPECT Aspirin Esomeprazole Chemoprevention trial

Phase: Open Type: NCRN
Contact Person Location Stage
Mr. Joseph RahamimPlymouth Hospitals NHS TrustClosed
Dr. Richard EllisRoyal Cornwall Hospitals NHS TrustClosed
Dr. Tawfique DaneshmendRoyal Devon & Exeter NHS Foundation TrustClosed
Dr. Cathryn EdwardsSouth Devon Healthcare NHS TrustClosed

BEST- BARRETT'S

Description:

BEST- BARRETT'S-Oesophagus Screening Trial

Phase: Open Type: NCRN
No current active trials.

BILCAP

Description:

BILCAP A randomised clinical trial evaluating adjuvant chemotherapy with capecitabine compared to expectant treatment alone following surgery for biliary tract cancer

Phase: Open Type: NCRN
Contact Person Location Stage
Dr Sarah PascoePlymouth Hospitals NHS TrustOpen

BOSS

Description:

BOSS -Barrett�s Oesophagus two yearly Surveillance versus no Surveillance: a randomised controlled trial to estimate effectiveness and cost-effectiveness

Phase: Open Type: NCRN
Contact Person Location Stage
Royal Cornwall Hospitals NHS TrustOpen

ChOPIN

Description:

ChOPIN-Chemoprevention of premalignant intestinal neoplasia (ChOPIN) incorporating inherited predisposition of neoplasia (IPOD) analysis of genomic DNA from AspECT and BOSS clinical trials.(co-adopted study-entry via Oral and Gastrointestinal teams).

Phase: Open Type: NCRN
Contact Person Location Stage
Northern Devon Healthcare NHS TrustOpen-via Gastrointestinal Team

COG

Description:

COG-Phase III randomised, double-blind, placebo-controlled trial of gefitinib (Iressa�) versus placebo in oesophageal cancer progressing after chemotherapy

Phase: In Setup Type: NCRN
Contact Person Location Stage
Dr Liz ToySouth Devon Healthcare NHS TrustOpen

ESPAC -Tplus

Description:

ESPAC -Tplus-Translational Studies

Phase: Open Type: NCRN
Contact Person Location Stage
Dr Mark NapierNorthern Devon Healthcare NHS TrustOpen
Dr Sarah PascoePlymouth Hospitals NHS TrustOpen
South Devon Healthcare NHS TrustOpen

ESPAC-3(v2)

Description:

ESPAC-3(v2) Phase III Adjuvant Trial in Pancreatic Cancer Comparing 5FU and D-L-Folinic Acid vs. Gemcitabine

Phase: Open Type: NCRN
Contact Person Location Stage
Dr. Mark NapierNorthern Devon Healthcare NHS TrustClosed
Dr. Francis DanielPlymouth Hospitals NHS TrustClosed
Dr. Elizabeth ToyRoyal Devon & Exeter NHS Foundation TrustClosed
Dr. Elizabeth ToySouth Devon Healthcare NHS TrustClosed

ESPAC-4

Description:

ESPAC-4-EUROPEAN STUDY GROUP FOR PANCREATIC CANCER - TRIAL 4. Combination versus single agent chemotherapy in resectable pancreatic cancer

Phase: Open Type: NCRN
Contact Person Location Stage
Dr Mark NapierNorthern Devon Healthcare NHS TrustOpen
Dr Sarah PascoePlymouth Hospitals NHS TrustOpen

OE05

Description:

OE05 A randomised controlled trial comparing standard chemotherapy followed by resection versus ECX chemotherapy followed by resection in patients with resectable adenocarcinoma of the oesophagus

Phase: Open Type: NCRN
Contact Person Location Stage
Dr. Sarah PascoePlymouth Hospitals NHS TrustOpen
Dr. Richard EllisRoyal Cornwall Hospitals NHS TrustOpen
Dr. Elizabeth ToyRoyal Devon & Exeter NHS Foundation TrustOpen
Dr. Elizabeth ToySouth Devon Healthcare NHS TrustOpen

REAL-3

Description:

REAL-3-A randomised open-labelled multicentre trial of the efficacy of epirubicin, oxaliplatin and capecitabine (EOX) with or without panitumumab in previously untreated advanced oesophago-gastric cancer (REAL3)

Phase: Open Type: NCRN
Contact Person Location Stage
Dr Mark NapierNorthern Devon Healthcare NHS TrustOpen

SOCS Stomach and Oesophageal Cancer Study(SOCS)

Description:

SOCS Stomach and Oesophageal Cancer Study(SOCS)-Establishment of a population-based resource to help identify the genetic and environmental determinants of oesophageal and gastric adenocarcinomas

Phase: Open Type: NCRN
Contact Person Location Stage
Dr Mark NapierNorthern Devon Healthcare NHS TrustOpen
Dr. Elizabeth ToyRoyal Devon & Exeter NHS Foundation TrustOpen
Dr Liz ToySouth Devon Healthcare NHS TrustOpen

ST03

Description:

ST03-A Randomised Phase III trial of Peri-operative Chemotherapy with or without Bevacizumab in Operable Adenocarcinoma of the Stomach and Gastro-oesophageal Junction

Phase: Open Type: NCRN
Contact Person Location Stage
Dr Sarah PascoePlymouth Hospitals NHS TrustOpen
Royal Cornwall Hospitals NHS TrustOpen
Royal Devon & Exeter NHS Foundation TrustOpen
Dr Liz ToySouth Devon Healthcare NHS TrustOpen

Telovac

Description:

TeloVac -A prospective, phase III, controlled, multicentre, randomised clinical trial comparing combination Gemcitabine and Capecitabine therapy with concurrent and sequential chemoimmunotherapy using a telomerase vaccine in locally advanced and metastati

Phase: Open Type: NCRN
Contact Person Location Stage
Dr Mark NapierNorthern Devon Healthcare NHS TrustOpen
Dr. Richard EllisRoyal Cornwall Hospitals NHS TrustOpen
Dr. Elizabeth ToyRoyal Devon & Exeter NHS Foundation TrustOpen
Dr. Elizabeth ToySouth Devon Healthcare NHS TrustOpen